E751 – Cystoscopy with insertion of chemotherapeutic agent(s)
OHIP Surgical Assists Code — UROGENITAL AND URINARY SURGICAL PROCEDURES · Schedule of Benefits
This service is an add-on to a primary cystoscopy procedure, such as Z606, and involves the insertion of one or more chemotherapeutic agents into the bladder. It is listed under the Diagnostic and Therapeutic Procedures for Endoscopy - Cystoscopy. As per the note on page of the Schedule, this code is not eligible for payment when billed with Z603 or Z611.
When to Use
- Use E751 as an add-on when performing an intravesical chemotherapy instillation (e.g., Mitomycin C or Gemcitabine) immediately following a diagnostic cystoscopy (Z606).
- Use E751 when the instillation of a chemotherapeutic agent is performed as part of a therapeutic cystoscopic procedure, provided the primary code is not Z603 or Z611.
Common Pitfalls
- Billing E751 alongside Z603 or Z611 will result in an automatic rejection as these codes are explicitly restricted per the Schedule of Benefits.
- Attempting to bill E751 as a standalone service will trigger a rejection; it must be submitted on the same claim as the primary cystoscopy procedure.
- Failure to document the specific chemotherapeutic agent used can lead to audit concerns regarding the clinical necessity of the add-on code.
Billing Tips
- Ensure the primary cystoscopy code (e.g., Z606) is listed first on the claim to establish the procedural context for the E751 add-on.
- If the procedure qualifies for after-hours premiums (E409 or E410), apply the percentage increase to the total fee, including the E751 component, provided the criteria for the premium are met.
Effective: April 1, 2026
T. Urogenital and Urinary Surgical Procedures
UROGENITAL AND URINARY SURGICAL PROCEDURES
Procedure
Urogenital and Urinary Surgical Procedures, Diagnostic and Therapeutic Procedures
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